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Initiation at AUGUG and GUGUG sequences can lead to translation of overlapping reading frames in E. coli

During initiation, the ribosome is tasked to efficiently recognize open reading frames (ORFs) for accurate and fast translation of mRNAs. A critical step is start codon recognition, which is modulated by initiation factors, mRNA structure, a Shine Dalgarno (SD) sequence and the start codon itself. W...

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Detalles Bibliográficos
Autores principales: Kohl, Maximilian P, Kompatscher, Maria, Clementi, Nina, Holl, Lena, Erlacher, Matthias D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841429/
https://www.ncbi.nlm.nih.gov/pubmed/36546769
http://dx.doi.org/10.1093/nar/gkac1175