Endothelial IK and SK channel activation decreases pulmonary arterial pressure and vascular remodeling in pulmonary hypertension

Endothelial cells (ECs) from small pulmonary arteries (PAs) release nitric oxide (NO) and prostacyclin, which lower pulmonary arterial pressure (PAP). In pulmonary hypertension (PH), the levels of endothelium‐derived NO and prostacyclin are reduced, contributing to elevated PAP. Small‐and intermedia...

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Detalles Bibliográficos
Autores principales: Daneva, Zdravka, Chen, Yen‐Lin, Ta, Huy Q., Manchikalapudi, Vamsi, Bazaz, Abhishek, Laubach, Victor E., Sonkusare, Swapnil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841469/
https://www.ncbi.nlm.nih.gov/pubmed/36686408
http://dx.doi.org/10.1002/pul2.12186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841469/
https://www.ncbi.nlm.nih.gov/pubmed/36686408
http://dx.doi.org/10.1002/pul2.12186

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