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Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy

Studies of mouse models of Alzheimer's disease (AD) have demonstrated that nitric oxide synthase 2 (NOS2) is involved in AD pathology. However, the effects of NOS2 on the pathology of Parkinson’s disease (PD) are not well studied. To address this gap, we examined the impact of NOS2 on disease-a...

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Detalles Bibliográficos
Autores principales: Kim, Jieun, Han, Jung-Youn, Lee, Yujeong, Kim, Kipom, Choi, Young Pyo, Chae, Sehyun, Hoe, Hyang-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841612/
https://www.ncbi.nlm.nih.gov/pubmed/36647152
http://dx.doi.org/10.1186/s13041-023-00996-1