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Integrated analysis of single-cell RNA-seq and bulk RNA-seq unveils heterogeneity and establishes a novel signature for prognosis and tumor immune microenvironment in ovarian cancer

Ovarian cancer is a highly heterogeneous gynecological malignancy that seriously affects the survival and prognosis of female patients. Single-cell sequencing and transcriptome analysis can effectively characterize tumor heterogeneity to better study the mechanism of occurrence and development. In t...

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Detalles Bibliográficos
Autores principales: Wang, Zitao, Zhang, Jie, Dai, Fangfang, Li, Bingshu, Cheng, Yanxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841625/
https://www.ncbi.nlm.nih.gov/pubmed/36642706
http://dx.doi.org/10.1186/s13048-022-01074-1