Cargando…

Integrated analysis of single-cell RNA-seq and bulk RNA-seq unveils heterogeneity and establishes a novel signature for prognosis and tumor immune microenvironment in ovarian cancer

Ovarian cancer is a highly heterogeneous gynecological malignancy that seriously affects the survival and prognosis of female patients. Single-cell sequencing and transcriptome analysis can effectively characterize tumor heterogeneity to better study the mechanism of occurrence and development. In t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zitao, Zhang, Jie, Dai, Fangfang, Li, Bingshu, Cheng, Yanxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841625/ https://www.ncbi.nlm.nih.gov/pubmed/36642706 http://dx.doi.org/10.1186/s13048-022-01074-1

Ejemplares similares

Integrative Analysis of Bulk RNA-Seq and Single-Cell RNA-Seq Unveils the Characteristics of the Immune Microenvironment and Prognosis Signature in Prostate Cancer
por: Wang, Ruisong, et al.
Publicado: (2022)

Unveiling mitophagy-mediated molecular heterogeneity and development of a risk signature model for colorectal cancer by integrated scRNA-seq and bulk RNA-seq analysis
por: Gao, Han, et al.
Publicado: (2023)

ScRNA-seq and bulk RNA-seq reveal the characteristics of ferroptosis and establish a risk signature in cholangiocarcinoma
por: Yao, Wenchao, et al.
Publicado: (2022)

Integration of scRNA-Seq and Bulk RNA-Seq to Analyse the Heterogeneity of Ovarian Cancer Immune Cells and Establish a Molecular Risk Model
por: Liang, Leilei, et al.
Publicado: (2021)

Identification and Verification of Necroptosis-Related Gene Signature With Prognosis and Tumor Immune Microenvironment in Ovarian Cancer
por: Wang, Zitao, et al.
Publicado: (2022)

Single-cell RNA-Seq unveils tumor microenvironment
por: Lee, Hae-Ock, et al.
Publicado: (2017)

Establishment of an ovarian cancer omentum metastasis-related prognostic model by integrated analysis of scRNA-seq and bulk RNA-seq
por: Zhang, Dongni, et al.
Publicado: (2022)

Integrative Analysis of Bulk RNA-Seq and Single-Cell RNA-Seq Unveils Novel Prognostic Biomarkers in Multiple Myeloma
por: Zhao, Jing, et al.
Publicado: (2022)

Single-Cell RNA-Seq and Bulk RNA-Seq Reveal Intratumoral Heterogeneity and Tumor Microenvironment Characteristics in Diffuse Large B-Cell Lymphoma
por: Zhao, Yang, et al.
Publicado: (2022)

Integration of scRNA-Seq and Bulk RNA-Seq Reveals Molecular Characterization of the Immune Microenvironment in Acute Pancreatitis
por: Fang, Zhen, et al.
Publicado: (2022)

Combined bulk RNA-seq and single-cell RNA-seq identifies a necroptosis-related prognostic signature associated with inhibitory immune microenvironment in glioma
por: Wan, Sicheng, et al.
Publicado: (2022)

Comprehensive analysis of scRNA-Seq and bulk RNA-Seq reveals dynamic changes in the tumor immune microenvironment of bladder cancer and establishes a prognostic model
por: Tan, Zhiyong, et al.
Publicado: (2023)

Delving into the Heterogeneity of Different Breast Cancer Subtypes and the Prognostic Models Utilizing scRNA-Seq and Bulk RNA-Seq
por: Xu, Jieyun, et al.
Publicado: (2022)

Integrated analysis of single-cell RNA-seq and bulk RNA-seq unravels the heterogeneity of cancer-associated fibroblasts in TNBC
por: Wu, Xiaoqing, et al.
Publicado: (2023)

Mast cell marker gene signature: prognosis and immunotherapy response prediction in lung adenocarcinoma through integrated scRNA-seq and bulk RNA-seq
por: Zhang, Pengpeng, et al.
Publicado: (2023)

Establishment and validation of an aging-related risk signature associated with prognosis and tumor immune microenvironment in breast cancer
por: Wang, Zitao, et al.
Publicado: (2022)

Integrating single-cell RNA-seq and bulk RNA-seq to construct prognostic signatures to explore the role of glutamine metabolism in breast cancer
por: Pei, Shengbin, et al.
Publicado: (2023)

Gene Mapping via Bulked Segregant RNA-Seq (BSR-Seq)
por: Liu, Sanzhen, et al.
Publicado: (2012)

SCRABBLE: single-cell RNA-seq imputation constrained by bulk RNA-seq data
por: Peng, Tao, et al.
Publicado: (2019)

Effective methods for bulk RNA-seq deconvolution using scnRNA-seq transcriptomes
por: Cobos, Francisco Avila, et al.
Publicado: (2023)

Integrated analysis of single-cell and bulk RNA-seq establishes a novel signature for prediction in gastric cancer
por: Wen, Fei, et al.
Publicado: (2023)

Analysis on heterogeneity of hepatocellular carcinoma immune cells and a molecular risk model by integration of scRNA-seq and bulk RNA-seq
por: Liu, Xiaorui, et al.
Publicado: (2022)

Exploring PANoptosis in breast cancer based on scRNA-seq and bulk-seq
por: He, Puxing, et al.
Publicado: (2023)

A Pyroptosis-Related Gene Signature Predicts Prognosis and Immune Microenvironment for Breast Cancer Based on Computational Biology Techniques
por: Wang, Zitao, et al.
Publicado: (2022)

An Efficient and Flexible Method for Deconvoluting Bulk RNA-Seq Data with Single-Cell RNA-Seq Data
por: Sun, Xifang, et al.
Publicado: (2019)

Comparative analyses of the prognosis, tumor immune microenvironment, and drug treatment response between left-sided and right-sided colon cancer by integrating scRNA-seq and bulk RNA-seq data
por: Cao, Lichao, et al.
Publicado: (2023)

Prime-seq, efficient and powerful bulk RNA sequencing
por: Janjic, Aleksandar, et al.
Publicado: (2022)

Construction of cancer- associated fibroblasts related risk signature based on single-cell RNA-seq and bulk RNA-seq data in bladder urothelial carcinoma
por: Liu, Yunxun, et al.
Publicado: (2023)

Single‐cell RNA‐seq and bulk RNA‐seq explore the prognostic value of exhausted T cells in hepatocellular carcinoma
por: Tang, Xiaolong, et al.
Publicado: (2023)

T-cell exhaustion signatures characterize the immune landscape and predict HCC prognosis via integrating single-cell RNA-seq and bulk RNA-sequencing
por: Chi, Hao, et al.
Publicado: (2023)

Integrated Analysis of Single-Cell RNA-Seq and Bulk RNA-Seq Combined with Multiple Machine Learning Identified a Novel Immune Signature in Diabetic Nephropathy
por: Peng, Yue-Ling, et al.
Publicado: (2023)

Mitochondrial DNA methylation is a predictor of immunotherapy response and prognosis in breast cancer: scRNA-seq and bulk-seq data insights
por: Ma, Yixuan, et al.
Publicado: (2023)

Deep learning using bulk RNA-seq data expands cell landscape identification in tumor microenvironment
por: Wang, Xin, et al.
Publicado: (2022)

Integration of scRNA-Seq and bulk RNA-Seq uncover perturbed immune cell types and pathways of Kawasaki disease
por: Cao, Naixin, et al.
Publicado: (2023)

Integrated analysis of single-cell RNA-seq and bulk RNA-seq reveals RNA N6-methyladenosine modification associated with prognosis and drug resistance in acute myeloid leukemia
por: Li, Zhongzheng, et al.
Publicado: (2023)

Unveiling functional heterogeneity in breast cancer multicellular tumor spheroids through single-cell RNA-seq
por: Muciño-Olmos, Erick Andrés, et al.
Publicado: (2020)

Characterization of cancer-related fibroblasts (CAF) in hepatocellular carcinoma and construction of CAF-based risk signature based on single-cell RNA-seq and bulk RNA-seq data
por: Yu, Lianghe, et al.
Publicado: (2022)

Integration of scRNA-Seq and TCGA RNA-Seq to Analyze the Heterogeneity of HPV+ and HPV- Cervical Cancer Immune Cells and Establish Molecular Risk Models
por: Wei, Erdong, et al.
Publicado: (2022)

Integration of single-cell and bulk RNA-seq to establish a predictive signature based on the differentiation trajectory of M2 macrophages in lung adenocarcinoma
por: Chen, Zhike, et al.
Publicado: (2022)

Prognosis and therapeutic benefits prediction based on NK cell marker genes through single-cell RNA-seq with integrated bulk RNA-seq analysis for hepatocellular carcinoma
por: Yang, Yao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_4rjnmt62j8d03mclet6n68tlip