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O-linked N-acetylglucosamine affects mitochondrial homeostasis by regulating Parkin-dependent mitophagy in hyperoxia-injured alveolar type II cells injury

BACKGROUND: The level of linked N-acetylglucosamine (O-GlcNAc) has been proved to be a sensor of cell state, but its relationship with hyperoxia-induced alveolar type 2 epithelial cells injure and bronchopulmonary dysplasia (BPD) has not been clarified. In this study, we evaluated if these effects u...

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Detalles Bibliográficos
Autores principales: Xuefei, Yu, Dongyan, Liu, Tianming, Li, Hejuan, Zheng, Jianhua, Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841680/
https://www.ncbi.nlm.nih.gov/pubmed/36647045
http://dx.doi.org/10.1186/s12931-022-02287-0