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Metabolic stress constrains microbial L-cysteine production in Escherichia coli by accelerating transposition through mobile genetic elements
BACKGROUND: L-cysteine is an essential chemical building block in the pharmaceutical-, cosmetic-, food and agricultural sector. Conventionally, L-cysteine production relies on the conversion of keratinous biomass mediated by hydrochloric acid. Today, fermentative production based on recombinant E. c...
Autores principales: | Heieck, Kevin, Arnold, Nathanael David, Brück, Thomas Bartholomäus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841684/ https://www.ncbi.nlm.nih.gov/pubmed/36642733 http://dx.doi.org/10.1186/s12934-023-02021-5 |
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