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Transcriptional signature in microglia isolated from an Alzheimer's disease mouse model treated with scanning ultrasound

Transcranial scanning ultrasound combined with intravenously injected microbubbles (SUS(+MB)) has been shown to transiently open the blood–brain barrier and reduce the amyloid‐β (Aβ) pathology in the APP23 mouse model of Alzheimer's disease (AD). This has been accomplished through the activatio...

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Detalles Bibliográficos
Autores principales: Leinenga, Gerhard, Bodea, Liviu‐Gabriel, Schröder, Jan, Sun, Giuzhi, Zhou, Yichen, Song, Jae, Grubman, Alexandra, Polo, Jose M., Götz, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842024/
https://www.ncbi.nlm.nih.gov/pubmed/36684089
http://dx.doi.org/10.1002/btm2.10329