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Osteopontin activity modulates sex‐specific calcification in engineered valve tissue mimics

Patients with aortic valve stenosis (AVS) have sexually dimorphic phenotypes in their valve tissue, where male valvular tissue adopts a calcified phenotype and female tissue becomes more fibrotic. The molecular mechanisms that regulate sex‐specific calcification in valvular tissue remain poorly unde...

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Detalles Bibliográficos
Autores principales: Schroeder, Megan E., Batan, Dilara, Gonzalez Rodriguez, Andrea, Speckl, Kelly F., Peters, Douglas K., Kirkpatrick, Bruce E., Hach, Grace K., Walker, Cierra J., Grim, Joseph C., Aguado, Brian A., Weiss, Robert M., Anseth, Kristi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842038/
https://www.ncbi.nlm.nih.gov/pubmed/36684107
http://dx.doi.org/10.1002/btm2.10358