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Osteopontin activity modulates sex‐specific calcification in engineered valve tissue mimics
Patients with aortic valve stenosis (AVS) have sexually dimorphic phenotypes in their valve tissue, where male valvular tissue adopts a calcified phenotype and female tissue becomes more fibrotic. The molecular mechanisms that regulate sex‐specific calcification in valvular tissue remain poorly unde...
Autores principales: | Schroeder, Megan E., Batan, Dilara, Gonzalez Rodriguez, Andrea, Speckl, Kelly F., Peters, Douglas K., Kirkpatrick, Bruce E., Hach, Grace K., Walker, Cierra J., Grim, Joseph C., Aguado, Brian A., Weiss, Robert M., Anseth, Kristi S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842038/ https://www.ncbi.nlm.nih.gov/pubmed/36684107 http://dx.doi.org/10.1002/btm2.10358 |
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