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Nanoalbumin–prodrug conjugates prepared via a thiolation‐and‐conjugation method improve cancer chemotherapy and immune checkpoint blockade therapy by promoting CD8 (+) T‐cell infiltration

Protein–drug conjugates are emerging tools to combat cancers. Here, we adopted an indirect thiolation‐and‐conjugation method as a general strategy to prepare protein–drug conjugates. We found for the first time that this method led to the formation of nanometric conjugates, probably due to the forma...

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Detalles Bibliográficos
Autores principales: Chen, Long, Xu, Nuo, Wang, Pan, Zhu, Haichuan, Zhang, Zijian, Yang, Zhanqun, Zhang, Wenyuan, Guo, Hongyan, Lin, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842047/
https://www.ncbi.nlm.nih.gov/pubmed/36684090
http://dx.doi.org/10.1002/btm2.10377