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Nanoalbumin–prodrug conjugates prepared via a thiolation‐and‐conjugation method improve cancer chemotherapy and immune checkpoint blockade therapy by promoting CD8 (+) T‐cell infiltration
Protein–drug conjugates are emerging tools to combat cancers. Here, we adopted an indirect thiolation‐and‐conjugation method as a general strategy to prepare protein–drug conjugates. We found for the first time that this method led to the formation of nanometric conjugates, probably due to the forma...
Autores principales: | Chen, Long, Xu, Nuo, Wang, Pan, Zhu, Haichuan, Zhang, Zijian, Yang, Zhanqun, Zhang, Wenyuan, Guo, Hongyan, Lin, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842047/ https://www.ncbi.nlm.nih.gov/pubmed/36684090 http://dx.doi.org/10.1002/btm2.10377 |
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