YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma

YAP is a transcriptional co-activator with critical roles in tumorigenesis. However, its upstream regulatory mechanism, especially how its mRNA stability is regulated, remains to be further studied. Here, we validated that YAP expression was higher in lung adenocarcinoma (LUAD) tissues compared to a...

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Detalles Bibliográficos
Autores principales: Yu, Wenjun, Zhang, Congcong, Wang, Yikun, Tian, Xiaoting, Miao, Yayou, Meng, Fanyu, Ma, Lifang, Zhang, Xiao, Xia, Jinjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842506/
https://www.ncbi.nlm.nih.gov/pubmed/36123390
http://dx.doi.org/10.1038/s41417-022-00533-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842506/
https://www.ncbi.nlm.nih.gov/pubmed/36123390
http://dx.doi.org/10.1038/s41417-022-00533-7

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