Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function

5-Lipoxygenase (5-LO), the central enzyme in the biosynthesis of leukotrienes, is frequently expressed in human solid malignancies even though the enzyme is not present in the corresponding healthy tissues. There is little knowledge on the consequences of this expression for the tumor cells regardin...

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Detalles Bibliográficos
Autores principales: Weisser, Hannah, Göbel, Tamara, Melissa Krishnathas, G., Kreiß, Marius, Angioni, Carlo, Sürün, Duran, Thomas, Dominique, Schmid, Tobias, Häfner, Ann-Kathrin, Kahnt, Astrid S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842508/
https://www.ncbi.nlm.nih.gov/pubmed/36114329
http://dx.doi.org/10.1038/s41417-022-00531-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842508/
https://www.ncbi.nlm.nih.gov/pubmed/36114329
http://dx.doi.org/10.1038/s41417-022-00531-9

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