Cargando…
Knock-out of 5-lipoxygenase in overexpressing tumor cells—consequences on gene expression and cellular function
5-Lipoxygenase (5-LO), the central enzyme in the biosynthesis of leukotrienes, is frequently expressed in human solid malignancies even though the enzyme is not present in the corresponding healthy tissues. There is little knowledge on the consequences of this expression for the tumor cells regardin...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842508/ https://www.ncbi.nlm.nih.gov/pubmed/36114329 http://dx.doi.org/10.1038/s41417-022-00531-9 |