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Using mechanism similarity to understand enzyme evolution
Enzyme reactions take place in the active site through a series of catalytic steps, which are collectively termed the enzyme mechanism. The catalytic step is thereby the individual unit to consider for the purposes of building new enzyme mechanisms — i.e. through the mix and match of individual cata...
Autores principales: | Ribeiro, António J. M., Riziotis, Ioannis G., Tyzack, Jonathan D., Borkakoti, Neera, Thornton, Janet M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842563/ https://www.ncbi.nlm.nih.gov/pubmed/36659981 http://dx.doi.org/10.1007/s12551-022-01022-9 |
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