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HDAC1-mediated regulation of GABA signaling within the lateral septum facilitates long-lasting social fear extinction in male mice

Social anxiety disorder (SAD) is caused by traumatic social experiences. It is characterized by intense fear and avoidance of social contexts, which can be robustly mimicked by the social fear conditioning (SFC) paradigm. The extinction phase of the SFC paradigm is akin to exposure therapy for SAD a...

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Detalles Bibliográficos
Autores principales: Bludau, Anna, Neumann, Inga D., Menon, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842607/
https://www.ncbi.nlm.nih.gov/pubmed/36646675
http://dx.doi.org/10.1038/s41398-023-02310-y