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Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex

The 22nd genetically encoded amino acid, pyrrolysine, plays a unique role in the key step in the growth of methanogens on mono-, di-, and tri-methylamines by activating the methyl group of these substrates for transfer to a corrinoid cofactor. Previous crystal structures of the Methanosarcina barker...

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Detalles Bibliográficos
Autores principales: Li, Jiaxin, Kang, Patrick T., Jiang, Ruisheng, Lee, Jodie Y., Soares, Jitesh A., Krzycki, Joseph A., Chan, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842639/
https://www.ncbi.nlm.nih.gov/pubmed/36646841
http://dx.doi.org/10.1038/s42003-022-04397-3