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mGluR5 is transiently confined in perisynaptic nanodomains to shape synaptic function
The unique perisynaptic distribution of postsynaptic metabotropic glutamate receptors (mGluRs) at excitatory synapses is predicted to directly shape synaptic function, but mechanistic insight into how this distribution is regulated and impacts synaptic signaling is lacking. We used live-cell and sup...
Autores principales: | Scheefhals, Nicky, Westra, Manon, MacGillavry, Harold D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842668/ https://www.ncbi.nlm.nih.gov/pubmed/36646691 http://dx.doi.org/10.1038/s41467-022-35680-w |
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