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Generation of myocyte agonal Ca(2+) waves and contraction bands in perfused rat hearts following irreversible membrane permeabilisation

Although irreversible cardiomyocyte injury provokes intracellular Ca(2+) ([Ca(2+)](i)) overload, the underlying dynamics of this response and its effects on cellular morphology remain unknown. We therefore visualised rapid-scanning confocal fluo4-[Ca(2+)](i) dynamics and morphology of cardiomyocytes...

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Detalles Bibliográficos
Autores principales: Morishita, Yuma, Tamura, Shoko, Mochizuki, Kentaro, Harada, Yoshinori, Takamatsu, Tetsuro, Hosoi, Hajime, Tanaka, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842683/
https://www.ncbi.nlm.nih.gov/pubmed/36646772
http://dx.doi.org/10.1038/s41598-023-27807-w