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Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis

While immunotherapy has emerged as a breakthrough cancer therapy, it is only effective in some patients, indicating the need of alternative therapeutic strategies. Induction of cancer immunogenic cell death (ICD) is one promising way to elicit potent adaptive immune responses against tumor-associate...

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Detalles Bibliográficos
Autores principales: Arimoto, Kei-ichiro, Miyauchi, Sayuri, Troutman, Ty D., Zhang, Yue, Liu, Mengdan, Stoner, Samuel A., Davis, Amanda G., Fan, Jun-Bao, Huang, Yi-Jou, Yan, Ming, Glass, Christopher K., Zhang, Dong-Er
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842760/
https://www.ncbi.nlm.nih.gov/pubmed/36646704
http://dx.doi.org/10.1038/s41467-022-35348-5