The metabolite alpha-ketobutyrate extends lifespan by promoting peroxisomal function in C. elegans

Metabolism is intimately linked to aging. There is a growing number of studies showing that endogenous metabolites may delay aging and improve healthspan. Through the analysis of existing transcriptome data, we discover a link between activation of the transsulfuration pathway and a transcriptional...

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Detalles Bibliográficos
Autores principales: Wu, Nan, Ma, Yi-Cheng, Gong, Xin-Qian, Zhao, Pei-Ji, Jia, Yong-Jian, Zhao, Qiu, Duan, Jia-Hong, Zou, Cheng-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842765/
https://www.ncbi.nlm.nih.gov/pubmed/36646719
http://dx.doi.org/10.1038/s41467-023-35899-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842765/
https://www.ncbi.nlm.nih.gov/pubmed/36646719
http://dx.doi.org/10.1038/s41467-023-35899-1

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