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HiC-GNN: A generalizable model for 3D chromosome reconstruction using graph convolutional neural networks

Chromosome conformation capture (3 C) is a method of measuring chromosome topology in terms of loci interaction. The Hi-C method is a derivative of 3 C that allows for genome-wide quantification of chromosome interaction. From such interaction data, it is possible to infer the three-dimensional (3D)...

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Detalles Bibliográficos
Autores principales: Hovenga, Van, Kalita, Jugal, Oluwadare, Oluwatosin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9842867/
https://www.ncbi.nlm.nih.gov/pubmed/36698967
http://dx.doi.org/10.1016/j.csbj.2022.12.051