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Targeting ryanodine receptors to treat human diseases
This Review provides an update on ryanodine receptors (RyRs) and their role in human diseases of heart, muscle, and brain. Calcium (Ca(2+)) is a requisite second messenger in all living organisms. From C. elegans to mammals, Ca(2+) is necessary for locomotion, bodily functions, and neural activity....
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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American Society for Clinical Investigation
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843046/ https://www.ncbi.nlm.nih.gov/pubmed/36647824 http://dx.doi.org/10.1172/JCI162891 |