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Targeting ryanodine receptors to treat human diseases

This Review provides an update on ryanodine receptors (RyRs) and their role in human diseases of heart, muscle, and brain. Calcium (Ca(2+)) is a requisite second messenger in all living organisms. From C. elegans to mammals, Ca(2+) is necessary for locomotion, bodily functions, and neural activity....

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Detalles Bibliográficos
Autor principal: Marks, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843046/
https://www.ncbi.nlm.nih.gov/pubmed/36647824
http://dx.doi.org/10.1172/JCI162891

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