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BMX controls 3βHSD1 and sex steroid biosynthesis in cancer

Prostate cancer is highly dependent on androgens and the androgen receptor (AR). Hormonal therapies inhibit gonadal testosterone production, block extragonadal androgen biosynthesis, or directly antagonize AR. Resistance to medical castration occurs as castration-resistant prostate cancer (CRPC) and...

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Detalles Bibliográficos
Autores principales: Li, Xiuxiu, Berk, Michael, Goins, Christopher, Alyamani, Mohammad, Chung, Yoon-Mi, Wang, Chenyao, Patel, Monaben, Rathi, Nityam, Zhu, Ziqi, Willard, Belinda, Stauffer, Shaun, Klein, Eric, Sharifi, Nima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843047/
https://www.ncbi.nlm.nih.gov/pubmed/36647826
http://dx.doi.org/10.1172/JCI163498