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Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients
BACKGROUND: The kynurenine pathway (KP) has been identified as a potential mediator linking acute illness to cognitive dysfunction by generating neuroactive metabolites in response to inflammation. Delirium (acute confusion) is a common complication of acute illness and is associated with increased...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843060/ https://www.ncbi.nlm.nih.gov/pubmed/36409557 http://dx.doi.org/10.1172/JCI163472 |