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Oncogenic KRAS signaling drives evasion of innate immune surveillance in lung adenocarcinoma by activating CD47

KRAS is one of the most frequently activated oncogenes in human cancers. Although the role of KRAS mutation in tumorigenesis and tumor maintenance has been extensively studied, the relationship between KRAS and the tumor immune microenvironment is not fully understood. Here, we identified a role of...

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Detalles Bibliográficos
Autores principales: Hu, Huanhuan, Cheng, Rongjie, Wang, Yanbo, Wang, Xiaojun, Wu, Jianzhuang, Kong, Yan, Zhan, Shoubin, Zhou, Zhen, Zhu, Hongyu, Yu, Ranran, Liang, Gaoli, Wang, Qingyan, Zhu, Xiaoju, Zhang, Chen-Yu, Yin, Rong, Yan, Chao, Chen, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843062/
https://www.ncbi.nlm.nih.gov/pubmed/36413402
http://dx.doi.org/10.1172/JCI153470