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Progress in fed-batch culture for recombinant protein production in CHO cells

ABSTRACT: Nearly 80% of the approved human therapeutic antibodies are produced by Chinese Hamster Ovary (CHO) cells. To achieve better cell growth and high-yield recombinant protein, fed-batch culture is typically used for recombinant protein production in CHO cells. According to the demand of nutri...

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Detalles Bibliográficos
Autores principales: Xu, Wen-Jing, Lin, Yan, Mi, Chun-Liu, Pang, Jing-Ying, Wang, Tian-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843118/
https://www.ncbi.nlm.nih.gov/pubmed/36648523
http://dx.doi.org/10.1007/s00253-022-12342-x