M2 macrophage-derived exosomal miR-145-5p protects against the hypoxia/reoxygenation-induced pyroptosis of cardiomyocytes by inhibiting TLR4 expression

BACKGROUND: Exosomes carrying micro ribonucleic acids (miRNAs) protect against myocardial ischemic injury. In the study, we sought to investigate the protective effect mechanism of M2 macrophage-derived exosome miR-145-5p in hypoxia-reoxygenation (H/R)-induced cardiomyocytes. METHODS: M2 macrophages...

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Detalles Bibliográficos
Autores principales: Wei, Li, Zhao, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843320/
https://www.ncbi.nlm.nih.gov/pubmed/36660616
http://dx.doi.org/10.21037/atm-22-6109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843320/
https://www.ncbi.nlm.nih.gov/pubmed/36660616
http://dx.doi.org/10.21037/atm-22-6109

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