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Tumor cell-derived exosomal microRNA-146a promotes non-small cell lung cancer cell invasion and proliferation by inhibiting M1 macrophage polarization

BACKGROUND: Tumor-associated macrophages (TAMs) affects the outcomes of non-small cell lung cancer (NSCLC). NSCLC cells released exosomes to suppress the antitumor activity of TAMs. MiR-146a is a critical regulator in TAM polarization. We hypothesized that NSCLC cells released exosomal miR-146a to r...

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Detalles Bibliográficos
Autores principales: Yan, Zhi, Wen, Jian-Xun, Cao, Xi-Shan, Zhao, Wen, Han, Yu-Ling, Wen, Xu-Hui, Yan, Li, Zhang, Man, Wang, Ya-Fei, Hai, Ling, Wang, Ying-Jun, Zheng, Wen-Qi, Hu, Zhi-De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843328/
https://www.ncbi.nlm.nih.gov/pubmed/36660623
http://dx.doi.org/10.21037/atm-22-5565