Idebenone reduces sepsis-induced oxidative stress and apoptosis in hepatocytes via RAGE/p38 signaling

BACKGROUND: Sepsis-induced liver dysfunction is believed to be an independent risk factor for multiple organ dysfunction and death. Idebenone (IDE), a synthetic analog of coenzyme Q10 (CoQ10), possesses an antioxidizing property. The present study aimed to investigate the efficacy of IDE on sepsis-i...

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Detalles Bibliográficos
Autores principales: Gou, Tao, Jin, Xiaoyu, Xia, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843342/
https://www.ncbi.nlm.nih.gov/pubmed/36660726
http://dx.doi.org/10.21037/atm-22-5758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843342/
https://www.ncbi.nlm.nih.gov/pubmed/36660726
http://dx.doi.org/10.21037/atm-22-5758

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