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Identifying the mechanisms and molecular targets of Hongjingtian injection on treatment of TGFβ1-induced HK-2 cells: coupling network pharmacology with experimental verification

BACKGROUND: The study was designed to investigate the mechanism of Hongjingtian injection (HJT) in treating tubulointerstitial fibrosis (TIF) in chronic kidney diseases (CKD) based on network pharmacology and experimental verification. METHODS: First, active ingredients of HJT obtained from literatu...

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Detalles Bibliográficos
Autores principales: Sun, Guanghui, Jiao, Mingwen, Cui, Yuying, Liang, Xuezhen, Liang, Xiaodong, Zhang, Shanshan, Guo, Congcong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843345/
https://www.ncbi.nlm.nih.gov/pubmed/36660701
http://dx.doi.org/10.21037/atm-22-5035