The peripheral Epac1/p-Cav-1 pathway underlies the disruption of the vascular endothelial barrier following skin/muscle incision and retraction-induced chronic postsurgical pain

BACKGROUND: Vascular endothelial barrier disruption is pivotal in the development of acute and chronic pain. Here, we demonstrate a previously unidentified molecular mechanism in which activation of the peripheral Epac1/p-Cav-1 pathway accelerated the disruption of the vascular endothelial barrier,...

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Detalles Bibliográficos
Autores principales: Chen, Hongsheng, She, Qing, Liu, Yanfang, Chen, Junjie, Qin, Yibin, Lu, Cui’e
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843368/
https://www.ncbi.nlm.nih.gov/pubmed/36660643
http://dx.doi.org/10.21037/atm-22-6069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843368/
https://www.ncbi.nlm.nih.gov/pubmed/36660643
http://dx.doi.org/10.21037/atm-22-6069

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