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SMC4 enhances the chemoresistance of hepatoma cells by promoting autophagy

BACKGROUND: Drug resistance is a major contributing factor to chemotherapy failure in hepatocellular carcinoma (HCC) patients. However, the exact mechanism underlying the chemoresistance of HCC remains unknown. METHODS: HepG2 cells were incubated with different concentrations of 5-fluorouracil (5-FU...

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Detalles Bibliográficos
Autores principales: Zhang, Shi-Ran, Li, Jie, Chen, Jing-Xiang, Chen, Geng, Chen, Jun-Ying, Fu, Hang-Wei, Zhou, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843382/
https://www.ncbi.nlm.nih.gov/pubmed/36660610
http://dx.doi.org/10.21037/atm-22-3623