A novel peptide HSP-17 ameliorates oxidative stress injury and apoptosis in H9c2 cardiomyocytes by activating the PI3K/Akt pathway

BACKGROUND: Oxidative stress and cell apoptosis play pivotal roles in the pathogenesis of doxorubicin (DOX)-induced myocardial injury. Heat shock protein-derived peptide (HSP-17) is a peptide which is low-expressed in DOX treated mouse heart tissue. It has high bioactivity and interspecies sequence...

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Detalles Bibliográficos
Autores principales: Chen, Xiaofang, Zhang, Hao, Feng, Mengwen, Xu, Zhongqing, Qian, Lingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843411/
https://www.ncbi.nlm.nih.gov/pubmed/36660735
http://dx.doi.org/10.21037/atm-22-6007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843411/
https://www.ncbi.nlm.nih.gov/pubmed/36660735
http://dx.doi.org/10.21037/atm-22-6007

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