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Posoleucel, an Allogeneic, Off-the-Shelf Multivirus-Specific T-Cell Therapy, for the Treatment of Refractory Viral Infections in the Post-HCT Setting

PURPOSE: Viral infections are a major cause of morbidity and mortality following allogeneic hematopoietic cell transplantation (allo-HCT). In the absence of safe and effective antiviral treatments, virus-specific T cells have emerged as a promising therapeutic option. Posoleucel is a multivirus-spec...

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Detalles Bibliográficos
Autores principales: Pfeiffer, Thomas, Tzannou, Ifigeneia, Wu, Mengfen, Ramos, Carlos, Sasa, Ghadir, Martinez, Caridad, Lulla, Premal, Krance, Robert A., Scherer, Lauren, Ruderfer, Daniel, Naik, Swati, Bocchini, Claire, Fraser, Iain P., Patel, Badrish, Ward, Dany, Wang, Tao, Heslop, Helen E., Leen, Ann M., Omer, Bilal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843433/
https://www.ncbi.nlm.nih.gov/pubmed/36628536
http://dx.doi.org/10.1158/1078-0432.CCR-22-2415