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Predicting Molecular Subtype and Survival of Rhabdomyosarcoma Patients Using Deep Learning of H&E Images: A Report from the Children's Oncology Group

PURPOSE: Rhabdomyosarcoma (RMS) is an aggressive soft-tissue sarcoma, which primarily occurs in children and young adults. We previously reported specific genomic alterations in RMS, which strongly correlated with survival; however, predicting these mutations or high-risk disease at diagnosis remain...

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Detalles Bibliográficos
Autores principales: Milewski, David, Jung, Hyun, Brown, G. Thomas, Liu, Yanling, Somerville, Ben, Lisle, Curtis, Ladanyi, Marc, Rudzinski, Erin R., Choo-Wosoba, Hyoyoung, Barkauskas, Donald A., Lo, Tammy, Hall, David, Linardic, Corinne M., Wei, Jun S., Chou, Hsien-Chao, Skapek, Stephen X., Venkatramani, Rajkumar, Bode, Peter K., Steinberg, Seth M., Zaki, George, Kuznetsov, Igor B., Hawkins, Douglas S., Shern, Jack F., Collins, Jack, Khan, Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843436/
https://www.ncbi.nlm.nih.gov/pubmed/36346688
http://dx.doi.org/10.1158/1078-0432.CCR-22-1663