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Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study

BACKGROUND: Genetic diversity in human leukocyte antigen (HLA) alleles across populations is a significant risk factor for drug-induced severe cutaneous adverse reactions (SCARs), e.g., carbamazepine (CBZ)- and lamotrigine (LTG)-induced Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis...

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Detalles Bibliográficos
Autores principales: Dastgheib, Ladan, Rostami, Farima, Gharesi-Fard, Behrouz, Asadi-Pooya, Ali Akbar, Namjoo, Saba, Tahmasebi, Foroozan, Hadibarhaghtalab, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843459/
https://www.ncbi.nlm.nih.gov/pubmed/36688194
http://dx.doi.org/10.30476/IJMS.2022.91192.2241