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Adaptive laboratory evolution of antimicrobial resistance in bacteria for genetic and phenotypic analyses

Adaptive laboratory evolution (ALE) of bacteria has the potential to provide many insights like revealing novel mechanisms of resistance and elucidating the impact of drug combinations and concentrations on AMR evolution. Here, we describe a step-by-step ALE protocol for the model bacterium Escheric...

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Detalles Bibliográficos
Autores principales: Vinchhi, Rhea, Jena, Chinmaya, Matange, Nishad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843481/
https://www.ncbi.nlm.nih.gov/pubmed/36625217
http://dx.doi.org/10.1016/j.xpro.2022.102005