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Adaptive laboratory evolution of antimicrobial resistance in bacteria for genetic and phenotypic analyses
Adaptive laboratory evolution (ALE) of bacteria has the potential to provide many insights like revealing novel mechanisms of resistance and elucidating the impact of drug combinations and concentrations on AMR evolution. Here, we describe a step-by-step ALE protocol for the model bacterium Escheric...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843481/ https://www.ncbi.nlm.nih.gov/pubmed/36625217 http://dx.doi.org/10.1016/j.xpro.2022.102005 |