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Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling

Synovial fibroblasts are the active and aggressive drivers in the progression of arthritis, but the cellular and molecular mechanisms remain unknown. Here, our results showed that regulator of G protein signaling 12 (RGS12) maintained ciliogenesis in synovial fibroblasts, which is critical for the d...

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Detalles Bibliográficos
Autores principales: Yuan, Gongsheng, Yang, Shu-ting, Yang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843488/
https://www.ncbi.nlm.nih.gov/pubmed/36700049
http://dx.doi.org/10.1016/j.omtn.2022.12.017