Multiple machine learning methods aided virtual screening of Na(V)1.5 inhibitors

Na(v)1.5 sodium channels contribute to the generation of the rapid upstroke of the myocardial action potential and thereby play a central role in the excitability of myocardial cells. At present, the patch clamp method is the gold standard for ion channel inhibitor screening. However, this method ha...

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Detalles Bibliográficos
Autores principales: Kong, Weikaixin, Huang, Weiran, Peng, Chao, Zhang, Bowen, Duan, Guifang, Ma, Weining, Huang, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843531/
https://www.ncbi.nlm.nih.gov/pubmed/36573431
http://dx.doi.org/10.1111/jcmm.17652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843531/
https://www.ncbi.nlm.nih.gov/pubmed/36573431
http://dx.doi.org/10.1111/jcmm.17652

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