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Multiple machine learning methods aided virtual screening of Na(V)1.5 inhibitors
Na(v)1.5 sodium channels contribute to the generation of the rapid upstroke of the myocardial action potential and thereby play a central role in the excitability of myocardial cells. At present, the patch clamp method is the gold standard for ion channel inhibitor screening. However, this method ha...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843531/ https://www.ncbi.nlm.nih.gov/pubmed/36573431 http://dx.doi.org/10.1111/jcmm.17652 |