CIC reduces xCT/SLC7A11 expression and glutamate release in glioma

Capicua (CIC) is an important downstream molecule of RTK/RAS/MAPK pathway. The regulatory mechanism of CIC underlying tumorigenesis in oligodendroglioma, where CIC is frequently mutated, has yet to be fully elucidated. Using patient-derived glioma lines, RNA-sequencing and bioinformatic analysis of...

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Detalles Bibliográficos
Autores principales: Park, Jong-Whi, Kilic, Omer, Deo, Minh, Jimenez-Cowell, Kevin, Demirdizen, Engin, Kim, Hyunggee, Turcan, Şevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843885/
https://www.ncbi.nlm.nih.gov/pubmed/36647117
http://dx.doi.org/10.1186/s40478-023-01507-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843885/
https://www.ncbi.nlm.nih.gov/pubmed/36647117
http://dx.doi.org/10.1186/s40478-023-01507-y

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