Comparing g-computation, propensity score-based weighting, and targeted maximum likelihood estimation for analyzing externally controlled trials with both measured and unmeasured confounders: a simulation study

OBJECTIVES: To have confidence in one's interpretation of treatment effects assessed by comparing trial results to external controls, minimizing bias is a critical step. We sought to investigate different methods for causal inference in simulated data sets with measured and unmeasured confounde...

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Detalles Bibliográficos
Autores principales: Ren, Jinma, Cislo, Paul, Cappelleri, Joseph C., Hlavacek, Patrick, DiBonaventura, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843888/
https://www.ncbi.nlm.nih.gov/pubmed/36647031
http://dx.doi.org/10.1186/s12874-023-01835-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843888/
https://www.ncbi.nlm.nih.gov/pubmed/36647031
http://dx.doi.org/10.1186/s12874-023-01835-6

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