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Comparing g-computation, propensity score-based weighting, and targeted maximum likelihood estimation for analyzing externally controlled trials with both measured and unmeasured confounders: a simulation study
OBJECTIVES: To have confidence in one's interpretation of treatment effects assessed by comparing trial results to external controls, minimizing bias is a critical step. We sought to investigate different methods for causal inference in simulated data sets with measured and unmeasured confounde...
Autores principales: | Ren, Jinma, Cislo, Paul, Cappelleri, Joseph C., Hlavacek, Patrick, DiBonaventura, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9843888/ https://www.ncbi.nlm.nih.gov/pubmed/36647031 http://dx.doi.org/10.1186/s12874-023-01835-6 |
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