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PU.1-CD23 signaling mediates pulmonary innate immunity against Aspergillus fumigatus infection by driving inflammatory response

BACKGROUND: Aspergillosis is a common cause of morbidity and mortality in immunocompromised populations. PU.1 is critical for innate immunity against Aspergillus fumigatus (AF) in macrophages. However, the molecular mechanism underlying PU.1 mediating immunity against AF infection in human alveolar...

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Detalles Bibliográficos
Autores principales: Wang, Min, Zhang, Ming, Qiu, Jiayong, Liu, Chenyang, Lou, Yao, Wang, Tongsheng, Zhang, Yingmin, Mao, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844028/
https://www.ncbi.nlm.nih.gov/pubmed/36650424
http://dx.doi.org/10.1186/s12865-023-00539-2