A Low-Molecular-Weight BDNF Mimetic, Dipeptide GSB-214, Prevents Memory Impairment in Rat Models of Alzheimer’s Disease

Brain-derived neurotrophic factor (BDNF) is known to be involved in the pathogenesis of Alzheimer’s disease (AD). However, the pharmacological use of full-length neurotrophin is limited, because of its macromolecular protein nature. A dimeric dipeptide mimetic of the BDNF loop 1, bis-(N-monosuccinyl...

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Detalles Bibliográficos
Autores principales: Povarnina, P. Yu., Volkova, A. A., Vorontsova, O. N., Kamensky, A. A., Gudasheva, T. A., Seredenin, S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844091/
https://www.ncbi.nlm.nih.gov/pubmed/36694902
http://dx.doi.org/10.32607/actanaturae.11755

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844091/
https://www.ncbi.nlm.nih.gov/pubmed/36694902
http://dx.doi.org/10.32607/actanaturae.11755

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