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A Low-Molecular-Weight BDNF Mimetic, Dipeptide GSB-214, Prevents Memory Impairment in Rat Models of Alzheimer’s Disease
Brain-derived neurotrophic factor (BDNF) is known to be involved in the pathogenesis of Alzheimer’s disease (AD). However, the pharmacological use of full-length neurotrophin is limited, because of its macromolecular protein nature. A dimeric dipeptide mimetic of the BDNF loop 1, bis-(N-monosuccinyl...
Autores principales: | Povarnina, P. Yu., Volkova, A. A., Vorontsova, O. N., Kamensky, A. A., Gudasheva, T. A., Seredenin, S. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
A.I. Gordeyev
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844091/ https://www.ncbi.nlm.nih.gov/pubmed/36694902 http://dx.doi.org/10.32607/actanaturae.11755 |
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