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Tris(4-azidophenyl)methanol – a novel and multifunctional thiol protecting group

The novel tris(4-azidophenyl)methanol, a multifunctionalisable aryl azide, is reported. The aryl azide can be used as a protecting group for thiols in peptoid synthesis and can be cleaved under mild reaction conditions via a Staudinger reduction. Moreover, the easily accessible aryl azide can be fun...

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Detalles Bibliográficos
Autores principales: Qiu, Xujun, Brückel, Julian, Zippel, Christoph, Nieger, Martin, Biedermann, Frank, Bräse, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9844210/
https://www.ncbi.nlm.nih.gov/pubmed/36741178
http://dx.doi.org/10.1039/d2ra05997e